Sodium Bicarbonate 8.4% Injection SDV 8.4% 50mL – Medex Supply

Description

Description

Key Features:

• Active Ingredient: Sodium Bicarbonate (NaHCO3): A potent alkalizing agent that dissociates into sodium (Na+) and bicarbonate (HCO3−) ions in the body.

• Concentration: 8.4%, which translates to 1 mEq (milliequivalent) of sodium bicarbonate per milliliter (1 mEq/mL). This is a highly concentrated solution, delivering 50 mEq of sodium bicarbonate in a 50 mL vial.

• Volume: 50 mL per single-dose glass flip-top vial. This larger volume is suitable for situations requiring rapid and significant bicarbonate administration.

• Preservative Free: This formulation does not contain any preservatives, which is crucial for intravenous administration and prevents potential adverse reactions associated with preservatives.

• Sterile and Nonpyrogenic: Ensures the solution is free from microorganisms and fever-producing substances.

• Hypertonic Solution: Its high concentration of solutes makes it hypertonic, meaning it has a higher osmolarity than human blood (approximately 2000 mOsmol/L). This property is important to consider during administration, as rapid infusion can lead to fluid shifts.

• pH: The solution generally has an approximate pH of 8.0 (ranging from 7.0 to 8.5).

• Single-Dose Vial: Designed for single use; any unused portion must be discarded to maintain sterility.

Uses:

• Treatment of Metabolic Acidosis: Its primary indication is for the treatment of metabolic acidosis, which can arise from various severe conditions, including:

  • Severe renal disease (kidney failure)

  • Uncontrolled diabetes (diabetic ketoacidosis)

  • Circulatory insufficiency due to shock or severe dehydration

  • Extracorporeal circulation of blood (e.g., during cardiopulmonary bypass)

  • Cardiac arrest

  • Severe primary lactic acidosis

  • Severe diarrhea (which can lead to significant bicarbonate loss)

• Certain Drug Intoxications: Used in the treatment of specific drug intoxications, such as:

  • Barbiturate poisoning (to promote dissociation of the barbiturate-protein complex)

  • Salicylate (aspirin) poisoning

  • Methyl alcohol poisoning

• Alkalinization of Urine: In hemolytic reactions, it can be used to alkalinize the urine to diminish the nephrotoxicity (kidney damage) of certain substances.

• Cardiac Arrest Management: A key component in advanced cardiac life support (ACLS) protocols for managing severe acidosis during cardiac arrest, although its use is specific and guided by blood gas analysis.

• Adjunctive Therapy: Used as an adjunct to other therapies to restore acid-base balance and support physiological functions during critical illness.