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Glutathione Reduced, Cell Culture Reagent, 98%, MP Biomedicals 25 g | Buy Online | MP Biomedicals, Inc | Fisher Scientific

Glutathione Reduced, Cell Culture Reagent, 98%, MP Biomedicals 25 g | Buy Online | MP Biomedicals, Inc | Fisher Scientific

Original price was: $255.20.Current price is: $146.29.

SKU: 0219467925 Category: Tag:

Description

Glutathione Reduced, Cell Culture Reagent, ≥98% is used for protein purification and elutes GST-tagged protein from glutathione agarose.

  • Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells.
  • It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
  • Glutathione is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst.
  • Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center.
  • Glutathione also forms disulfide bonds with cysteine residues in proteins.
  • Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
  • Typical Working Concentration: May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

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